ZBTB16

Also known as PLZF, ZNF145, zinc finger and BTB domain containing 16

protein-coding gene in the species Homo sapiens

In the Vinony graph

Within Vinony's link graph, ZBTB16 is referenced by 832 other articles, and connects out to PubMed, Ensembl genome database project and homeobox.

Vinony files it under Genes on human chromosome 11 and Transcription factors.

Its subject is documented across 7 Wikipedia language editions.

Gene data

ZBTB16

Name: zinc finger and BTB domain containing 16
Type: protein-coding
Position: 114,058,335–114,256,765 (+)
Aliases: PLZF, ZNF145
Ensembl: ENSG00000109906
RefSeq RNA: NM_001018011.3, NM_001354750.2, NM_001354751.2, NM_001354752.1, NM_006006.6
RefSeq protein: NP_001018011.1, NP_001341679.1, NP_001341680.1, NP_001341681.1, NP_005997.2

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].