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Sulfoxone
Sign in to saveAlso known as Aldesulfone, Aldesulphone
Sulfoxone or aldesulfone sodium is an anti-leprosy drug. It is also known as diasone. Diasone is mentioned as an anti-leprosy drug in the 1961 movie "The Devil At 4 O'clock". Sulfoxone sodium was introduced in Japan in 1948. Ernest Muir introduced it to Western use while serving as superintendent of the Chacachacare Leprosarium on Trinidad in the Caribbean.
Chemical data
- Formula
- C14H16N2O6S3
- Molecular weight
- 404.5 g/mol
- IUPAC name
- [4-[4-(sulfinomethylamino)phenyl]sulfonylanilino]methanesulfinic acid
- SMILES
- C1=CC(=CC=C1NCS(=O)O)S(=O)(=O)C2=CC=C(C=C2)NCS(=O)O
- InChIKey
- NEDPPCHNEOMTJV-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 180 Ų
- H-bond donors
- 4
- H-bond acceptors
- 10
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- oral
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 404.017049
Show 2 more facts
- chemical formula
- C₁₄H₁₆N₂O₆S₃
- canonical SMILES
- C1=CC(=CC=C1NCS(=O)O)S(=O)(=O)C2=CC=C(C=C2)NCS(=O)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Sulfoxone or aldesulfone sodium is an anti-leprosy drug. It is also known as diasone. Diasone is mentioned as an anti-leprosy drug in the 1961 movie "The Devil At 4 O'clock". Sulfoxone sodium was introduced in Japan in 1948. Ernest Muir introduced it to Western use while serving as superintendent of the Chacachacare Leprosarium on Trinidad in the Caribbean.
==References==
Excerpted from Wikipedia’s “Sulfoxone” article, available under the CC BY-SA 4.0 licence.