SUMO1

Also known as DAP1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3

Small ubiquitin-related modifier 1 is a protein that in humans is encoded by the SUMO1 gene.

Gene data

SUMO1

Name: small ubiquitin like modifier 1
Type: protein-coding
Aliases: DAP1, GMP1, OFC10, PIC1, SMT3, SMT3C, SMT3H3, UBL1

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].

via MyGene.info