Structure via PubChem · Public domain (PubChem)
tametraline
Sign in to saveTametraline (CP-24,441) is the parent of a series of chemical compounds investigated at Pfizer that eventually led to the development of sertraline.
Chemical data
- Formula
- C17H19N
- Molecular weight
- 237.34 g/mol
- IUPAC name
- (1R,4S)-N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine
- SMILES
- CN[C@@H]1CC[C@H](C2=CC=CC=C12)C3=CC=CC=C3
- InChIKey
- NVXPZMLRGBVYQV-WMLDXEAASA-N
- XLogP
- 3.5
- Polar surface area
- 12 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 237.151749608
Show 4 more facts
- chemical formula
- C₁₇H₁₉N
- Commons category
- Tametraline
- canonical SMILES
- CNC1CCC(C2=CC=CC=C12)C3=CC=CC=C3
- isomeric SMILES
- CN[C@@H]1CC[C@H](C2=CC=CC=C12)C3=CC=CC=C3
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Tametraline (CP-24,441) is the parent of a series of chemical compounds investigated at Pfizer that eventually led to the development of sertraline.
Sertraline has been called "3,4-dichloro-tametraline". This is correct but it is an oversimplification in the sense that sertraline is the S,S-isomer whereas tametraline is the 1R,4S-stereoisomer.
Excerpted from Wikipedia’s “tametraline” article, available under the CC BY-SA 4.0 licence.