TDRD3

Also known as tudor domain containing 3

Tudor domain-containing protein 3 is a protein that in humans is encoded by the TDRD3 gene. It contains a Tudor domain and UBA protein domain and has three distinct Protein isoforms.

Gene data

TDRD3

Name: tudor domain containing 3
Type: protein-coding
Position: 60,396,457–60,573,879 (+)
Ensembl: ENSG00000083544
RefSeq RNA: NM_001146070.2, NM_001146071.1, NM_030794.2, XM_005266556.5, XM_005266560.3
RefSeq protein: NP_001139542.1, NP_001139543.1, NP_110421.1, XP_005266613.1, XP_005266617.1

Enables chromatin binding activity; methylated histone binding activity; and transcription coactivator activity. Predicted to be involved in chromatin organization and positive regulation of transcription, DNA-templated. Located in Golgi apparatus; cytosol; and nucleoplasm. Colocalizes with exon-exon junction complex. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

DNA topological change positive regulation of DNA-templated transcription siRNA-mediated heterochromatin formation

Molecular function

chromatin binding transcription coactivator activity RNA binding RNA binding protein binding histone H3 reader activity histone H4 reader activity histone H4 reader activity

Cellular component

nucleus nucleus nucleus nucleoplasm cytoplasm cytosol exon-exon junction complex DNA topoisomerase III-beta-TDRD3 complex

via MyGene.info

Gene · Ensembl

tudor domain containing 3

Symbol: TDRD3
Biotype: Protein coding
Organism: Homo sapiens
Location: 13:60,396,457-60,573,879
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein TDRD3 PDB 1wji.png

Show 5 more facts

HomoloGene ID: 12771
exact match: identifiers.org/ncbigene/81550
genomic end: 61148012
genomic start: 60970591
cytogenetic location: 13q21.2

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Further reading

Tudor domain-containing protein 3 is a protein that in humans is encoded by the TDRD3 gene. It contains a Tudor domain and UBA protein domain and has three distinct Protein isoforms.

==References==