CASC3
Sign in to saveAlso known as BTZ, MLN51, cancer susceptibility candidate 3, cancer susceptibility 3, CASC3, exon junction complex subunit, CASC3 exon junction complex subunit
Protein CASC3 is a protein that in humans is encoded by the CASC3 gene.
Gene data
CASC3- Name
- CASC3 exon junction complex subunit
- Type
- protein-coding
- Position
- 40,140,278–40,177,001 (+)
- Aliases
- BTZ, MLN51
- Ensembl
- ENSG00000108349
- RefSeq RNA
- NM_007359.5, XM_005257163.3, XM_047435623.1, XM_047435624.1, XM_054315480.1
- RefSeq protein
- NP_031385.2, XP_005257220.1, XP_047291579.1, XP_047291580.1, XP_054171455.1
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CASC3 exon junction complex subunit
- Symbol
- CASC3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:40,140,278-40,177,001
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- The crystal structure of the human Exon Junction Complex 2J0S CASC3.png
Show 5 more facts
- HomoloGene ID
- 7208
- exact match
- identifiers.org/ncbigene/22794
- genomic end
- 40172171
- genomic start
- 38296571
- cytogenetic location
- 17q21.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- References
- External links
- Further reading
Protein CASC3 is a protein that in humans is encoded by the CASC3 gene.
== Function ==