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GeneQ18031815· pop 5· linked from 7 articles

Also known as HH10, NKB, NKNB, PRO1155, ZNEUROK1, tachykinin 3, tachykinin precursor 3, NK3

Tachykinin-3 is a protein that in humans is encoded by the TAC3 gene.

Gene data

TAC3
Name
tachykinin precursor 3
Type
protein-coding
Aliases
HH10, LncZBTB39, NK3, NKB, NKNB, PRO1155, ZNEUROK1

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016].

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Gene · Ensembl

tachykinin precursor 3

Symbol
TAC3
Biotype
Protein coding
Organism
Homo sapiens
Location
12:57,010,000-57,028,883
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
7560
genomic end
57422667
genomic start
57403784
cytogenetic location
12q13.3
Sources (4)

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Contents
  • See also
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  • Further reading

Tachykinin-3 is a protein that in humans is encoded by the TAC3 gene.

==See also== Neurokinin B Tachykinin receptor 3

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