TAC3
Sign in to saveAlso known as HH10, NKB, NKNB, PRO1155, ZNEUROK1, tachykinin 3, tachykinin precursor 3, NK3
Tachykinin-3 is a protein that in humans is encoded by the TAC3 gene.
In the Vinony graph
Within Vinony's link graph, TAC3 is referenced by 7 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Its subject is documented across 5 Wikipedia language editions.
Gene data
TAC3- Name
- tachykinin precursor 3
- Type
- protein-coding
- Position
- 57,010,000–57,028,883 (−)
- Aliases
- HH10, LncZBTB39, NK3, NKB, NKNB, PRO1155, ZNEUROK1
- Ensembl
- ENSG00000166863
- RefSeq RNA
- NM_001006667.1, NM_001178054.2, NM_013251.4, NR_033654.2, NR_135164.2
- RefSeq protein
- NP_001171525.1, NP_037383.1
This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
tachykinin precursor 3
- Symbol
- TAC3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:57,010,000-57,028,883
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 7560
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6866
- genomic end
- 57422667
- genomic start
- 57403784
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.3
- expressed in
- testicle
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Tachykinin-3 is a protein that in humans is encoded by the TAC3 gene.
==See also== Neurokinin B Tachykinin receptor 3
Excerpted from Wikipedia’s “TAC3” article, available under the CC BY-SA 4.0 licence.