ORC3
Sign in to saveAlso known as LAT, LATHEO, ORC3L, origin recognition complex subunit 3
Origin recognition complex subunit 3 is a protein that in humans is encoded by the ORC3 (ORC3L) gene.
In the Vinony graph
Vinony's link graph records 90 inbound references to ORC3, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under topics including Genes on human chromosome 6 and Protein pages needing a picture.
Vinony links it to 7 Wikipedia language editions.
Gene data
ORC3- Name
- origin recognition complex subunit 3
- Type
- protein-coding
- Position
- 87,590,067–87,681,796 (+)
- Aliases
- LATHEO, ORC3L
- Ensembl
- ENSG00000135336
- RefSeq RNA
- NM_001197259.2, NM_012381.4, NM_181837.3, XM_005248704.3, XM_011535651.3
- RefSeq protein
- NP_001184188.1, NP_036513.2, NP_862820.1, XP_005248761.1, XP_011533953.1
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
origin recognition complex subunit 3
- Symbol
- ORC3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:87,590,067-87,681,796
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8225
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23595
- genomic end
- 88377169
- genomic start
- 88299839
- chromosome
- human chromosome 6
- cytogenetic location
- 6q15
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Origin recognition complex subunit 3 is a protein that in humans is encoded by the ORC3 (ORC3L) gene.
== Function ==
Excerpted from Wikipedia’s “ORC3” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0