Structure via PubChem · Public domain (PubChem)
tertatolol
Sign in to saveAlso known as S-2395, Artex, Artexal, Prenalex
Tertatolol (Artex, Artexal, Prenalex) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It was discovered by the French pharmaceutical company Servier and is marketed in Europe.
In the Vinony graph
Within Vinony's link graph, tertatolol is referenced by 1,718 other articles, and connects out to propranolol, adrenergic receptor and N-methylserotonin.
It sits within the topics 5-HT1A antagonists, 5-HT1B antagonists and Beta blockers.
Its subject is documented across 11 Wikipedia language editions.
Chemical data
- Formula
- C16H25NO2S
- Molecular weight
- 295.4 g/mol
- IUPAC name
- 1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol
- SMILES
- CC(C)(C)NCC(COC1=CC=CC2=C1SCCC2)O
- InChIKey
- HTWFXPCUFWKXOP-UHFFFAOYSA-N
- XLogP
- 2.7
- Polar surface area
- 66.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
179 papers- Overview of clinical safety and efficacy of tertatolol.Cardiology · 1993
- Tertatolol: a beta-blocker with unique effects on human glomerular cell function.Cardiology · 1993
- Overview of novel renal properties of tertatolol.Cardiology · 1993
- Tertatolol-induced lupus.Arthritis and rheumatism · 1988
- Biodisposition of tertatolol in man: a review.American journal of nephrology · 1986
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 295.1606
Show 4 more facts
- subject has role
- antiarrhythmic agent
- chemical formula
- C₁₆H₂₅NO₂S
- canonical SMILES
- CC(C)(C)NCC(COC1=CC=CC2=C1SCCC2)O
- defined daily dose
- 5
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Tertatolol (Artex, Artexal, Prenalex) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It was discovered by the French pharmaceutical company Servier and is marketed in Europe.
Tertatolol has also been shown to act as a serotonin 5-HT1A and 5-HT1B receptor antagonist, similarly to propranolol and pindolol.
Excerpted from Wikipedia’s “tertatolol” article, available under the CC BY-SA 4.0 licence.