thiotepa
Thiotepa (N,N',N''(-triethylenethiophosphoramide, INN), sold under the brand name Tepadina among others, is an anti-cancer medication.
Chemical data
- Formula
- C6H12N3PS
- Molecular weight
- 189.22 g/mol
- IUPAC name
- tris(aziridin-1-yl)-sulfanylidene-lambda5-phosphane
- SMILES
- C1CN1P(=S)(N2CC2)N3CC3
- InChIKey
- FOCVUCIESVLUNU-UHFFFAOYSA-N
- XLogP
- 0.5
- Polar surface area
- 41.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
3,849 papersArticle
14 sectionsContents
- History
- Structure
- Reactivity
- Synthesis
- Medical uses
- Administration
- Clinical outcomes
- Metabolism
- Molecular mechanism of action
- Toxicity
- Myelosuppression
- Additional toxic effects
- Drug interactions
- References
Thiotepa (N,N',N''(-triethylenethiophosphoramide, INN), sold under the brand name Tepadina among others, is an anti-cancer medication.
Thiotepa is an organophosphorus compound with the formula (C2H4N)3PS.
Gallery (4)
Connections
Categories
1-Aziridinyl compoundsAlkylating antineoplastic agentsCancer treatmentsCYP2B6 inhibitorsDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs with non-standard legal statusECHA InfoCard ID from WikidataIARC Group 1 carcinogensInfobox drug articles with non-default infobox titleOrganophosphoric amides