File:Thyroxine2.svg · Wikimedia Commons · See Wikimedia Commons
thyroxine
Sign in to saveAlso known as DL-thyroxine
Thyroxine, also known as T4, is a hormone produced by the thyroid gland. It is the primary form of thyroid hormone found in the blood and acts as a prohormone of the more active thyroid hormone, triiodothyronine (T3). Thyroxine and its active metabolites are essential for regulating metabolic rate, supporting heart and muscle function, promoting brain development, and maintaining bone health.
Chemical data
- Formula
- C15H11I4NO4
- Molecular weight
- 776.87 g/mol
- IUPAC name
- 2-azaniumyl-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
- SMILES
- C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])[NH3+]
- InChIKey
- XUIIKFGFIJCVMT-UHFFFAOYSA-N
- XLogP
- 3
- Polar surface area
- 97.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
66,778 papers- Thyroxine's evolutionary roots.Perspectives in biology and medicine · 1997
- A short review on the role of thyroxine in fast wound healing and tissue regeneration.Tissue & cell · 2023
- DIETARY thyroxine and hypothyroidism.Nutrition reviews · 1953
- Recent developments with thyroxine.The Pharmaceutical journal · 1949
- A bivariate reference interval for TSH and free thyroxine.Scandinavian journal of clinical and laboratory investigation · 2024
via PubMed
Wikidata facts
- Mass
- 776.686699832
Show 3 more facts
- canonical SMILES
- O=C(O)C(N)CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1
- chemical formula
- C₁₅H₁₁I₄NO₄
- Commons category
- Thyroxine
Sources (5)
via Wikidata · CC0
~2 min read
Article
3 sectionsContents
- Regulation
- Biosynthesis
- References
Thyroxine, also known as T4, is a hormone produced by the thyroid gland. It is the primary form of thyroid hormone found in the blood and acts as a prohormone of the more active thyroid hormone, triiodothyronine (T3). Thyroxine and its active metabolites are essential for regulating metabolic rate, supporting heart and muscle function, promoting brain development, and maintaining bone health.
== Regulation ==