Also known as 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C
protein-coding gene in the species Homo sapiens
Gene data
TNC- Name
- tenascin C
- Type
- protein-coding
- Position
- 115,019,575–115,118,257 (−)
- Aliases
- 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C
- Ensembl
- ENSG00000041982
- RefSeq RNA
- NM_001410991.1, NM_001439065.1, NM_001439066.1, NM_001439067.1, NM_001439068.1
- RefSeq protein
- NP_001397920.1, NP_001425994.1, NP_001425995.1, NP_001425996.1, NP_001425997.1
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration. [provided by RefSeq, Jul 2011].
Gene Ontology
Biological process
Molecular function
Pathways
PI3K-Akt signaling pathway - Homo sapiens (human)Focal adhesion - Homo sapiens (human)ECM-receptor interaction - Homo sapiens (human)Human papillomavirus infection - Homo sapiens (human)MicroRNAs in cancer - Homo sapiens (human)Extracellular matrix organizationExtracellular matrix organizationIntegrin cell surface interactionsSyndecan interactionsNon-integrin membrane-ECM interactions
via MyGene.info
Gene · Ensembl
tenascin C
- Symbol
- TNC
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:115,019,575-115,118,257
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein TNC PDB 1ten.png
Show 5 more facts
- HomoloGene ID
- 55636
- exact match
- identifiers.org/ncbigene/3371
- genomic end
- 117880536
- genomic start
- 115019575
- cytogenetic location
- 9q33.1
via Wikidata · CC0
Connections
Q180686
Entity
base pair
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oligomer
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human chromosome 9
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Ensembl genome database project
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