Structure via PubChem · Public domain (PubChem)
tolfenamic acid
Sign in to saveAlso known as N-(3-chloro-2-methylphenyl)anthranilic acid, N-(2-methyl-3-chlorophenyl)anthranilic acid, N-(3-chloro-o-tolyl)-anthranilic acid
chemical compound
In the Vinony graph
Within Vinony's link graph, tolfenamic acid is referenced by 1,450 other articles, and connects out to valproic acid, N-methylserotonin and salicylic acid.
It is catalogued under topics including Anthranilic acids, Antipyretics and Chloroarenes.
Its subject is documented across 15 Wikipedia language editions.
Chemical data
- Formula
- C14H12ClNO2
- Molecular weight
- 261.7 g/mol
- IUPAC name
- 2-(3-chloro-2-methylanilino)benzoic acid
- SMILES
- CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O
- InChIKey
- YEZNLOUZAIOMLT-UHFFFAOYSA-N
- XLogP
- 5.2
- Polar surface area
- 49.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- rheumatic disease, pancreatic carcinoma, progressive supranuclear palsy
via ChEMBL · EBI
Research
471 papers- Tolfenamic Acid.Profiles of drug substances, excipients, and related methodology · 2018
- Chemopreventive Properties of Tolfenamic Acid: A Mechanistic Review.Current medicinal chemistry · 2018
- Tolfenamic acid negatively regulates YAP and TAZ expression in human cancer cells.Biochimica et biophysica acta. Molecular cell research · 2023
- Tolfenamic acid and leukotriene synthesis inhibition.Pharmacology & toxicology · 1994
- Copper-tolfenamic acid: evaluation of stability and anti-cancer activity.Investigational new drugs · 2019
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 261.056
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₄H₁₂ClNO₂
- canonical SMILES
- CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O
- World Health Organisation international non-proprietary name
- tolfenamic acid
- Commons category
- Tolfenamic acid
Sources (2)
via Wikidata · CC0
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via Wikidata sitelinks · CC0
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