TRAP1
Sign in to saveAlso known as HSP 75, HSP75, HSP90L, TRAP-1, TNF receptor associated protein 1
Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene.
Gene data
TRAP1- Name
- TNF receptor associated protein 1
- Type
- protein-coding
- Position
- 3,651,639–3,717,591 (−)
- Aliases
- HSP 75, HSP75, HSP90L, TRAP-1
- Ensembl
- ENSG00000126602
- RefSeq RNA
- NM_001272049.2, NM_016292.3, XM_011522345.3, XM_054379372.1
- RefSeq protein
- NP_001258978.1, NP_057376.2, XP_011520647.1, XP_054235347.1
This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
TNF receptor associated protein 1
- Symbol
- TRAP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:3,651,639-3,717,595
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9457
- exact match
- identifiers.org/ncbigene/10131
- genomic end
- 3717553
- genomic start
- 3701640
- cytogenetic location
- 16p13.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Interactions
- References
- Further reading
- External links
Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene.
==Interactions== TRAP1 has been shown to interact with EXT2, EXT1 and Retinoblastoma protein.