TRIM3
Sign in to saveAlso known as BERP, HAC1, RNF22, RNF97, tripartite motif containing 3
Tripartite motif-containing protein 3 is a protein that in humans is encoded by the TRIM3 gene.
Gene data
TRIM3- Name
- tripartite motif containing 3
- Type
- protein-coding
- Aliases
- BERP, HAC1, RNF22, RNF97
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
tripartite motif containing 3
- Symbol
- TRIM3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:6,448,613-6,474,459
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 21290
- exact match
- identifiers.org/ncbigene/10612
- genomic start
- 6469843
- genomic end
- 6495689
- cytogenetic location
- 11p15.4
Sources (3)
via Wikidata · CC0
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Article
3 sectionsContents
- Interactions
- References
- Further reading
Tripartite motif-containing protein 3 is a protein that in humans is encoded by the TRIM3 gene.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.