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GeneQ18046253· pop 7· linked from 2 articles

TUT7

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Also known as PAPD6, zinc finger CCHC-type containing 6, TENT3B, ZCCHC6, terminal uridylyl transferase 7

Terminal uridylyltransferase 7 (TUT7), also known as "zinc finger, CCHC domain containing 6", is an enzyme that in humans is encoded by the ZCCHC6 gene located on chromosome 9. The ZCCHC6 protein mediates the terminal uridylation of RNA transcripts with short poly-A tails and is involved in mRNA and microRNA degradation

Gene data

TUT7
Name
terminal uridylyl transferase 7
Type
protein-coding
Position
86,287,725–86,354,810 (−)
Aliases
PAPD6, TENT3B, ZCCHC6
Ensembl
ENSG00000083223
RefSeq RNA
NM_001185059.2, NM_001185074.2, NM_001330718.2, NM_024617.4, XM_005252207.4
RefSeq protein
NP_001171988.1, NP_001172003.1, NP_001317647.1, NP_078893.2, XP_005252264.1

Enables RNA uridylyltransferase activity and miRNA binding activity. Involved in RNA metabolic process and negative regulation of transposition, RNA-mediated. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Pathways

Developmental BiologyDeadenylation-dependent mRNA decayDeadenylation of mRNAMetabolism of RNAMaternal to zygotic transition (MZT)Zygotic genome activation (ZGA)Z-decay: degradation of maternal mRNAs by zygotically expressed factors

via MyGene.info

Gene · Ensembl

terminal uridylyl transferase 7

Symbol
TUT7
Biotype
Protein coding
Organism
Homo sapiens
Location
9:86,287,725-86,354,810
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
51941
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/79670
genomic end
88969369
genomic start
88902648
chromosome
human chromosome 9
cytogenetic location
9q21.33
Commons category
TUT7
Sources (3)

via Wikidata · CC0

~2 min read

Encyclopedic overview

4 sections
Contents
  • Structure
  • Function
  • References
  • Further reading

Terminal uridylyltransferase 7 (TUT7), also known as "zinc finger, CCHC domain containing 6", is an enzyme that in humans is encoded by the ZCCHC6 gene located on chromosome 9. The ZCCHC6 protein mediates the terminal uridylation of RNA transcripts with short poly-A tails and is involved in mRNA and microRNA degradation

== Structure==

Excerpted from Wikipedia’s “TUT7” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0