Skip to content
Vinony
English
EnglishDeutschEspañolFrançaisItalianoNederlandsPortuguêsSvenskaالعربية
GeneQ18032259· pop 5· linked from 108 articles

UBE2G1

Sign in to save

Also known as E217K, UBC7, UBE2G, ubiquitin conjugating enzyme E2 G1

Ubiquitin-conjugating enzyme E2 G1 is a protein that in humans is encoded by the UBE2G1 gene.

Gene data

UBE2G1
Name
ubiquitin conjugating enzyme E2 G1
Type
protein-coding
Position
4,269,221–4,366,678 (−)
Aliases
E217K, UBC7, UBE2G
Ensembl
ENSG00000132388
RefSeq RNA
NM_003342.5, NM_182682.2
RefSeq protein
NP_003333.1

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

Ubiquitin mediated proteolysis - Homo sapiens (human)Protein processing in endoplasmic reticulum - Homo sapiens (human)Parkinson disease - Homo sapiens (human)Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)Adaptive Immune SystemImmune SystemMetabolism of proteinsPost-translational protein modificationProtein ubiquitinationSynthesis of active ubiquitin: roles of E1 and E2 enzymes

via MyGene.info

Gene · Ensembl

ubiquitin conjugating enzyme E2 G1

Symbol
UBE2G1
Biotype
Protein coding
Organism
Homo sapiens
Location
17:4,269,221-4,366,678
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Ubiquitin-conjugating enzyme E2 G1 is a protein that in humans is encoded by the UBE2G1 gene.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins.

Excerpted from Wikipedia’s “UBE2G1” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0