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ultrafiltration
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ultrafiltration

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Also known as UF

Ultrafiltration (UF) is a variety of membrane filtration in which forces such as pressure or concentration gradients lead to a separation through a semipermeable membrane. Suspended solids and solutes of high molecular weight are retained in the so-called retentate, while water and low molecular weight solutes pass through the membrane in the permeate (filtrate). This separation process is used in industry and research for purifying and concentrating macromolecular (103–106 Da) solutions, especially protein solutions.

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Ultrafiltration
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~16 min read

Article

35 sections
Contents
  • Applications
  • Drinking water
  • Protein concentration
  • Other applications
  • Principles
  • Membrane fouling
  • Concentration polarization
  • Types of fouling
  • Types of Foulants
  • Particulate deposition
  • Scaling
  • Biofouling
  • Membrane arrangements
  • Tubular modules
  • Hollow fibre
  • Spiral-wound modules
  • Plate and frame
  • Process characteristics
  • Process design considerations
  • Pre-treatment
  • Membrane specifications
  • Material
  • Pore size
  • Operation strategy
  • Flowtype
  • Flow velocity
  • Flow temperature
  • Pressure
  • Multi-stage, multi-module
  • Post-treatment
  • Cleaning
  • New developments
  • See also
  • References
  • External links

Ultrafiltration (UF) is a variety of membrane filtration in which forces such as pressure or concentration gradients lead to a separation through a semipermeable membrane. Suspended solids and solutes of high molecular weight are retained in the so-called retentate, while water and low molecular weight solutes pass through the membrane in the permeate (filtrate). This separation process is used in industry and research for purifying and concentrating macromolecular (103–106 Da) solutions, especially protein solutions.

Ultrafiltration is not fundamentally different from microfiltration. Both of these are separate based on size exclusion or particle capture. It is fundamentally different from membrane gas separation, which separate based on different amounts of absorption and different rates of diffusion. Ultrafiltration membranes are defined by the molecular weight cut-off (MWCO) of the membrane used. Ultrafiltration is applied in cross-flow or dead-end mode.

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