vanoxerine
Sign in to saveAlso known as GBR 12909, GBR12909, 1-{2-[bis(p-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine
Vanoxerine is an investigational drug which is being evaluated for the treatment of heart arrhythmias and cocaine dependence. Vanoxerine is a piperazine derivative which has multiple pharmacological activities including acting as an dopamine reuptake inhibitor, serotonin transporter inhibitor, and as a blocker of the cardiac hERG repolarizing potassium channel (IKr).
Research
530 papersvia PubMed
Wikidata facts
- Mass
- 450.24827
Show 4 more facts
- chemical formula
- C₂₈H₃₂F₂N₂O
- canonical SMILES
- C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F
- World Health Organisation international non-proprietary name
- vanoxerine
- Commons category
- Vanoxerine
Sources (2)
via Wikidata · CC0
~7 min read
Article
12 sectionsContents
- Research
- Treatment of cocaine dependence
- Antiarrhythmic
- Miscellaneous
- Pharmacology
- Mechanism of action
- Society and culture
- History
- Chemistry
- Synthesis
- See also
- References
Vanoxerine is an investigational drug which is being evaluated for the treatment of heart arrhythmias and cocaine dependence. Vanoxerine is a piperazine derivative which has multiple pharmacological activities including acting as an dopamine reuptake inhibitor, serotonin transporter inhibitor, and as a blocker of the cardiac hERG repolarizing potassium channel (IKr).
== Research ==