VAV2

Also known as VAV-2, vav guanine nucleotide exchange factor 2

Guanine nucleotide exchange factor VAV2 is a protein that in humans is encoded by the VAV2 gene.

Gene data

VAV2

Name: vav guanine nucleotide exchange factor 2
Type: protein-coding
Position: 133,761,892–133,992,854 (−)
Aliases: VAV-2
Ensembl: ENSG00000160293
RefSeq RNA: NM_001134398.2, NM_001411028.1, NM_003371.4, XM_017015108.2, XM_017015109.2
RefSeq protein: NP_001127870.1, NP_001397957.1, NP_003362.2, XP_016870597.1, XP_016870598.1

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

Gene Ontology

Biological process

immune response-regulating cell surface receptor signaling pathway signal transduction

Article

4 sections

Contents

Interactions
References
Further reading
External links

Guanine nucleotide exchange factor VAV2 is a protein that in humans is encoded by the VAV2 gene.

VAV2 is the second member of the VAV oncogene family. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues.