WNT11
Sign in to saveAlso known as HWNT11, Wnt family member 11
Protein Wnt-11 is a protein that in humans is encoded by the WNT11 gene.
Gene data
WNT11- Name
- Wnt family member 11
- Type
- protein-coding
- Position
- 76,186,325–76,210,762 (−)
- Aliases
- HWNT11
- Ensembl
- ENSG00000085741
- RefSeq RNA
- NM_004626.3, XM_005274231.2, XM_011545238.2, XM_011545239.3, XM_011545240.3
- RefSeq protein
- NP_004617.2, XP_005274288.1, XP_011543540.1, XP_011543541.1, XP_011543542.1
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
Wnt family member 11
- Symbol
- WNT11
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:76,186,325-76,210,762
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 20970
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7481
- genomic end
- 75921780
- genomic start
- 75897369
- chromosome
- human chromosome 11
- cytogenetic location
- 11q13.5
- expressed in
- tendon
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Protein Wnt-11 is a protein that in humans is encoded by the WNT11 gene.
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein showing 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene plays roles in the development of bones, kidneys, and lungs, and is associated with early onset osteoporosis.
Excerpted from Wikipedia’s “WNT11” article, available under the CC BY-SA 4.0 licence.