ZFYVE27

Also known as PROTRUDIN, SPG33, zinc finger FYVE-type containing 27

Zinc finger, FYVE domain containing 27 is a protein that in humans is encoded by the ZFYVE27 gene.

In the Vinony graph

Vinony's link graph records 4 inbound references to ZFYVE27, and connects out to PubMed, human chromosome 10 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 10.

Vinony links it to 6 Wikipedia language editions.

Gene data

ZFYVE27

Name: zinc finger FYVE-type containing 27
Type: protein-coding
Position: 97,737,111–97,760,907 (+)
Aliases: PROTRUDIN, SPG33
Ensembl: ENSG00000155256
RefSeq RNA: NM_001002261.4, NM_001002262.4, NM_001174119.2, NM_001174120.2, NM_001174121.2
RefSeq protein: NP_001002261.1, NP_001002262.1, NP_001167590.1, NP_001167591.1, NP_001167592.1

This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010].