ZFYVE16

Also known as PPP1R69, zinc finger FYVE-type containing 16

Zinc finger FYVE domain-containing protein 16 is a protein that in humans is encoded by the ZFYVE16 gene.

In the Vinony graph

Vinony's link graph records 3 inbound references to ZFYVE16, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 5.

Vinony links it to 5 Wikipedia language editions.

Gene data

ZFYVE16

Name: zinc finger FYVE-type containing 16
Type: protein-coding
Position: 80,407,149–80,483,379 (+)
Aliases: PPP1R69
Ensembl: ENSG00000039319
RefSeq RNA: NM_001105251.4, NM_001284236.3, NM_001284237.2, NM_001349434.2, NM_014733.6
RefSeq protein: NP_001098721.2, NP_001271165.2, NP_001271166.2, NP_001336363.2, NP_055548.4

This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].

Pathways

Endocytosis - Homo sapiens (human)TGF-beta signaling pathway - Homo sapiens (human)Signal Transduction Signaling by BMP Signaling by TGFB family members TGF-beta Signaling Pathway

via MyGene.info

Gene · Ensembl

zinc finger FYVE-type containing 16

Symbol: ZFYVE16
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:80,407,149-80,483,379
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 8826
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/9765
genomic end: 80483379
genomic start: 79703832
chromosome: human chromosome 5
cytogenetic location: 5q14.1

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

Interactions
References
Further reading

Zinc finger FYVE domain-containing protein 16 is a protein that in humans is encoded by the ZFYVE16 gene.

The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It is characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle of the molecule.

Excerpted from Wikipedia’s “ZFYVE16” article, available under the CC BY-SA 4.0 licence.