ZHX3

Also known as TIX1, zinc fingers and homeoboxes 3

Zinc fingers and homeoboxes protein 3 is a protein that in humans is encoded by the ZHX3 gene.

In the Vinony graph

Vinony's link graph records 3 inbound references to ZHX3, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 20.

Vinony links it to 7 Wikipedia language editions.

Gene data

ZHX3

Name: zinc fingers and homeoboxes 3
Type: protein-coding
Position: 41,178,448–41,317,783 (−)
Aliases: TIX1
Ensembl: ENSG00000174306
RefSeq RNA: NM_001384315.1, NM_001384316.1, NM_001384317.1, NM_001384318.1, NM_001384319.1
RefSeq protein: NP_001371244.1, NP_001371245.1, NP_001371246.1, NP_001371247.1, NP_001371248.1

This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

regulation of transcription by RNA polymerase II positive regulation of osteoblast differentiation negative regulation of DNA-templated transcription

Molecular function

DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding protein homodimerization activity protein heterodimerization activity

Cellular component

chromatin nucleus nucleus nucleus nucleus nucleoplasm

via MyGene.info

Gene · Ensembl

zinc fingers and homeoboxes 3

Symbol: ZHX3
Biotype: Protein coding
Organism: Homo sapiens
Location: 20:41,178,448-41,317,783
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein ZHX3 PDB 2da5.png

Show 8 more facts

HomoloGene ID: 9000
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/23051
genomic end: 39946312
genomic start: 39807088
chromosome: human chromosome 20
cytogenetic location: 20q12
expressed in: nucleus accumbens

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

2 sections

Contents

References
Further reading

Zinc fingers and homeoboxes protein 3 is a protein that in humans is encoded by the ZHX3 gene.

This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded Protein contains two C2H2-type zinc fingers and five Homeodomains and forms a Dimer with itself or with Zinc fingers and homeoboxes family member 1. In the Nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor.fx

Excerpted from Wikipedia’s “ZHX3” article, available under the CC BY-SA 4.0 licence.