ACTL7A
Sign in to saveAlso known as actin like 7A
Actin-like protein 7A is a protein that in humans is encoded by the ACTL7A gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to ACTL7A, and connects out to PubMed, base pair and human chromosome 9.
Vinony files it under Genes on human chromosome 9 and Human proteins.
Vinony links it to 5 Wikipedia language editions.
Gene data
ACTL7A- Name
- actin like 7A
- Type
- protein-coding
- Position
- 108,862,266–108,863,756 (+)
- Aliases
- SPGF86
- Ensembl
- ENSG00000187003
- RefSeq RNA
- NM_006687.4
- RefSeq protein
- NP_006678.1
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
via MyGene.info
Gene · Ensembl
actin like 7A
- Symbol
- ACTL7A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:108,862,266-108,863,756
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 7613
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10881
- genomic end
- 108863756
- genomic start
- 111624603
- chromosome
- human chromosome 9
- cytogenetic location
- 9q31.3
- expressed in
- muscular system
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Actin-like protein 7A is a protein that in humans is encoded by the ACTL7A gene.
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
Excerpted from Wikipedia’s “ACTL7A” article, available under the CC BY-SA 4.0 licence.