ADH4
Sign in to saveAlso known as ADH-2, HEL-S-4, alcohol dehydrogenase 4 (class II), pi polypeptide
Alcohol dehydrogenase 4 is an enzyme that in humans is encoded by the ADH4 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to ADH4, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 4.
Vinony links it to 6 Wikipedia language editions.
Gene data
ADH4- Name
- alcohol dehydrogenase 4 (class II), pi polypeptide
- Type
- protein-coding
- Position
- 99,123,502–99,157,792 (−)
- Aliases
- ADH-2, HEL-S-4
- Ensembl
- ENSG00000198099
- RefSeq RNA
- NM_000670.5, NM_001306171.2, NM_001306172.2
- RefSeq protein
- NP_000661.2, NP_001293100.1, NP_001293101.1
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
alcohol dehydrogenase 4 (class II), pi polypeptide
- Symbol
- ADH4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:99,123,502-99,157,792
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- ADH4 prot.png
Show 8 more facts
- exact match
- identifiers.org/ncbigene/127
- found in taxon
- Homo sapiens
- HomoloGene ID
- 20162
- genomic end
- 100078949
- genomic start
- 100044808
- chromosome
- human chromosome 4
- cytogenetic location
- 4q23
- Commons category
- Alcohol dehydrogenase 4
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Alcohol dehydrogenase 4 is an enzyme that in humans is encoded by the ADH4 gene.
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
Excerpted from Wikipedia’s “ADH4” article, available under the CC BY-SA 4.0 licence.