AHSP

Name

alpha hemoglobin stabilizing protein

Type

protein-coding

Position

31,527,876–31,528,803 (+)

Aliases

EDRF, ERAF

Ensembl

ENSG00000169877

RefSeq RNA

NM_001318221.2, NM_001318222.2, NM_016633.4

RefSeq protein

NP_001305150.1, NP_001305151.1, NP_057717.1

This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].