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allolactose

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EntityQ3560955· pop 15· linked from 10 articles

allolactose

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Allolactose is a disaccharide similar to lactose. It consists of the monosaccharides D-galactose and D-glucose linked through a β1-6 glycosidic linkage instead of the β1-4 linkage of lactose. It may arise from the occasional transglycosylation of lactose by β-galactosidase.

In the Vinony graph

Within Vinony's link graph, allolactose is referenced by 10 other articles, and connects out to mass density, Wayback Machine and glucose.

It sits within the topics Chembox image size set and Disaccharides.

Its subject is documented across 14 Wikipedia language editions.

Chemical data

Formula
C12H22O11
Molecular weight
342.3 g/mol
IUPAC name
(3R,4S,5S,6R)-6-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxane-2,3,4,5-tetrol
SMILES
C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H](C(O2)O)O)O)O)O)O)O)O
InChIKey
DLRVVLDZNNYCBX-VDGMBKLFSA-N
XLogP
-4.7
Polar surface area
190 Ų
H-bond donors
8
H-bond acceptors
11
Formal charge
0

via PubChem

Wikidata facts

Subclass of
disaccharide
Has part
hydrogen
Mass
342.116212
Show 5 more facts
chemical formula
C₁₂H₂₂O₁₁
canonical SMILES
C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)O)O)O)O)O)O)O)O
isomeric SMILES
C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H](C(O2)O)O)O)O)O)O)O)O
Commons category
Allolactose
found in taxon
Escherichia coli
Sources (1)

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Encyclopedic overview

4 sections
Contents
  • Role in lac operon modeling
  • See also
  • References
  • External links

Allolactose is a disaccharide similar to lactose. It consists of the monosaccharides D-galactose and D-glucose linked through a β1-6 glycosidic linkage instead of the β1-4 linkage of lactose. It may arise from the occasional transglycosylation of lactose by β-galactosidase.

It is an inducer of the lac operon in Escherichia coli and many other enteric bacteria. It binds to a subunit of the tetrameric lac repressor, which results in conformational changes and reduces the binding affinity of the lac repressor to the lac operator, thereby dissociating it from the lac operator. The absence of the repressor allows the transcription of the lac operon to proceed.

Excerpted from Wikipedia’s “allolactose” article, available under the CC BY-SA 4.0 licence.

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