beta-galactosidase
Sign in to saveAlso known as beta-gal, β-gal, Β-galactosidase, beta-D-galactanase, trilactase, beta-D-galactoside galactohydrolase, exo-(1->4)-beta-D-galactanase, beta-lactosidase
β-Galactosidase (EC 3.2.1.23, beta-gal or β-gal; systematic name β-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyzes hydrolysis of terminal non-reducing β-D-galactose residues in β-D-galactosides. (This enzyme digests many β-Galactosides, not just lactose. It is sometimes loosely referred to as lactase but that name is generally reserved for mammalian digestive enzymes that break down lactose specifically.)
In the Vinony graph
Within Vinony's link graph, beta-galactosidase is referenced by 500 other articles, and connects out to PubMed, PubMed Central and isopropyl β-D-thiogalactopyranoside.
Vinony files it under Aging-related enzymes, Carbohydrate metabolism and EC 3.2.1.
Its subject is documented across 15 Wikipedia language editions.
Key facts
- Enzyme.Name
- β-Galactosidase
- Enzyme.EC_number
- 3.2.1.23
- Enzyme.CAS_number
- 9031-11-2
- Enzyme.GO_code
- 0009341
- Enzyme.image
- Beta-galactosidase (1tg7).png
- Enzyme.caption
- β-galactosidase from Penicillium sp. (from PDB )
- Enzyme.name
- β-Galactosidase
- Protein.Name
- galactosidase, beta 1
- Protein.HGNCid
- 4298
- Protein.Symbol
- GLB1
- Protein.AltSymbols
- ELNR1
- Protein.EntrezGene
- 2720
- Protein.OMIM
- 230500
- Protein.RefSeq
- NM_000404
- Protein.UniProt
- P16278
- Protein.Chromosome
- 3
- Protein.Arm
- p
- Protein.Band
- 22.3
via Wikipedia infobox
Research
38,696 papers- Senescence-associated beta-galactosidase is lysosomal beta-galactosidase.Aging cell · 2006
- β-Galactosidase.Cold Spring Harbor protocols · 2017
- Pharmacological Chaperones for β-Galactosidase Related to G(M1) -Gangliosidosis and Morquio B: Recent Advances.Chemical record (New York, N.Y.) · 2021
- Galantase (beta-galactosidase) treatment in pediatric practice.Therapia Hungarica (English edition) · 1989
- β-Galactosidase from Exiguobacterium acetylicum: Cloning, expression, purification and characterization.Bioresource technology · 2019
via PubMed
Wikidata facts
- Subclass of
- glycoside hydrolase superfamily
- Image
- Beta-galactosidase (1tg7).png
Show 2 more facts
- Commons category
- Beta-galactosidase
- EC enzyme number
- 3.2.1.23
Sources (2)
via Wikidata · CC0
~12 min read
Encyclopedic overview
8 sectionsContents
- Function
- Structure
- Reaction
- Applications
- Evolution
- Species distribution
- References
- External links
β-Galactosidase (EC 3.2.1.23, beta-gal or β-gal; systematic name β-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyzes hydrolysis of terminal non-reducing β-D-galactose residues in β-D-galactosides. (This enzyme digests many β-Galactosides, not just lactose. It is sometimes loosely referred to as lactase but that name is generally reserved for mammalian digestive enzymes that break down lactose specifically.)
β-Galactosides include carbohydrates containing galactose where the glycosidic bond lies above the galactose molecule. Substrates of different β-galactosidases include ganglioside GM1, lactosylceramides, lactose, and various glycoproteins.
Excerpted from Wikipedia’s “beta-galactosidase” article, available under the CC BY-SA 4.0 licence.