Structure via PubChem · Public domain (PubChem)
allylglycine
Sign in to saveAlso known as allyl glycine, DL-allylglycine
Allylglycine is a glycine derivative. It is an inhibitor of glutamate decarboxylase. Inhibition of glutamate decarboxylase blocks GABA biosynthesis, leading to lower levels of the neurotransmitter. Allylglycine is known to induce seizures in animals studies, presumably due to this GDC-inhibiting activity.
Chemical data
- Formula
- C5H9NO2
- Molecular weight
- 115.13 g/mol
- IUPAC name
- 2-aminopent-4-enoic acid
- SMILES
- C=CCC(C(=O)O)N
- InChIKey
- WNNNWFKQCKFSDK-UHFFFAOYSA-N
- XLogP
- -2.3
- Polar surface area
- 63.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
276 papers- Choline chloride and N-allylglycine promote plant growth by increasing the efficiency of photosynthesis.Bioscience, biotechnology, and biochemistry · 2024
- D-2-allylglycine embedded imidazolium-bridged polyhedral oligomeric silsesquioxane hybrid monolithic column for efficient separation of both small molecules and macromolecules.Journal of chromatography. A · 2020
- Bicuculline- and allylglycine-induced epilepsy in developing rats.Experimental neurology · 1985
- Synthesis of Polycyclic Tetrahydroisoquinolines and Tetrahydrobenzo[d]azepines from Polymer-Supported Allylglycine.The Journal of organic chemistry · 2022
- Convulsant properties of allylglycine.Life sciences · 1965
via PubMed
Wikidata facts
- Mass
- 115.063329
Show 2 more facts
- canonical SMILES
- C=CCC(C(=O)O)N
- chemical formula
- C₅H₉NO₂
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Allylglycine is a glycine derivative. It is an inhibitor of glutamate decarboxylase. Inhibition of glutamate decarboxylase blocks GABA biosynthesis, leading to lower levels of the neurotransmitter. Allylglycine is known to induce seizures in animals studies, presumably due to this GDC-inhibiting activity.
==See also== 3-Mercaptopropionic acid
Excerpted from Wikipedia’s “allylglycine” article, available under the CC BY-SA 4.0 licence.