ANKRD17

Also known as GTAR, NY-BR-16, MASK2, ankyrin repeat domain 17, CAGS

Ankyrin repeat domain-containing protein 17 is a protein that in humans is encoded by the ANKRD17 gene.

Gene data

ANKRD17

Name: ankyrin repeat domain 17
Type: protein-coding
Position: 73,073,376–73,259,169 (−)
Aliases: CAGS, GTAR, MASK2, NY-BR-16
Ensembl: ENSG00000132466
RefSeq RNA: NM_001286771.3, NM_015574.2, NM_032217.5, NM_198889.3, XM_005265671.5
RefSeq protein: NP_001273700.1, NP_056389.1, NP_115593.3, NP_942592.1, XP_005265728.1

The protein encoded by this gene belongs to the family of ankyrin repeat-containing proteins, and contains two distinct arrays of ankyrin repeats in its amino-terminal region, one with 15 ankyrin repeats, and the other with 10 ankyrin repeats. It also contains a nuclear export signal, nuclear localization signal, and a cyclin-binding RXL motif. Localization of this protein to the nucleus has been shown experimentally, and interactions between this protein and cyclin-dependent kinase 2 have been observed. It has been suggested that this protein plays a role in both DNA replication and in both anti-viral and anti-bacterial innate immune pathways. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].

via MyGene.info

Gene · Ensembl

ankyrin repeat domain 17

Symbol: ANKRD17
Biotype: Protein coding
Organism: Homo sapiens
Location: 4:73,073,376-73,259,169
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 82403
exact match: identifiers.org/ncbigene/26057
found in taxon: Homo sapiens
genomic end: 74124515
genomic start: 73939093
chromosome: human chromosome 4
cytogenetic location: 4q13.3
expressed in: pylorus

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

References
External links
Further reading

Ankyrin repeat domain-containing protein 17 is a protein that in humans is encoded by the ANKRD17 gene.

This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies in mice suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have been found for this gene.

Excerpted from Wikipedia’s “ANKRD17” article, available under the CC BY-SA 4.0 licence.