ANKRD17
Sign in to saveAlso known as GTAR, NY-BR-16, MASK2, ankyrin repeat domain 17, CAGS
Ankyrin repeat domain-containing protein 17 is a protein that in humans is encoded by the ANKRD17 gene.
Gene data
ANKRD17- Name
- ankyrin repeat domain 17
- Type
- protein-coding
- Aliases
- CAGS, GTAR, MASK2, NY-BR-16
The protein encoded by this gene belongs to the family of ankyrin repeat-containing proteins, and contains two distinct arrays of ankyrin repeats in its amino-terminal region, one with 15 ankyrin repeats, and the other with 10 ankyrin repeats. It also contains a nuclear export signal, nuclear localization signal, and a cyclin-binding RXL motif. Localization of this protein to the nucleus has been shown experimentally, and interactions between this protein and cyclin-dependent kinase 2 have been observed. It has been suggested that this protein plays a role in both DNA replication and in both anti-viral and anti-bacterial innate immune pathways. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].
via MyGene.info
Gene · Ensembl
ankyrin repeat domain 17
- Symbol
- ANKRD17
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:73,073,376-73,259,169
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 82403
- exact match
- identifiers.org/ncbigene/26057
- genomic end
- 74124515
- genomic start
- 73939093
- cytogenetic location
- 4q13.3
Sources (3)
via Wikidata · CC0
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Article
3 sectionsContents
- References
- External links
- Further reading
Ankyrin repeat domain-containing protein 17 is a protein that in humans is encoded by the ANKRD17 gene.
This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies in mice suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have been found for this gene.