BASP1
Sign in to saveAlso known as CAP-23, CAP23, NAP-22, NAP22, brain abundant membrane attached signal protein 1
thumb|Friedrich Miescher Institute on Novartis St. Johann Campus Brain acid soluble protein 1 is a protein that in humans is encoded by the BASP1 gene.
Gene data
BASP1- Name
- brain abundant membrane attached signal protein 1
- Type
- protein-coding
- Aliases
- CAP-23, CAP23, NAP-22, NAP22
This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2012].
via MyGene.info
Gene · Ensembl
brain abundant membrane attached signal protein 1
- Symbol
- BASP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:17,065,598-17,276,857
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 38168
- exact match
- identifiers.org/ncbigene/10409
- genomic start
- 17065707
- genomic end
- 17276943
- cytogenetic location
- 5p15.1
Sources (3)
via Wikidata · CC0
~8 min read
Article
9 sectionsContents
- Discovery
- Structure
- Function
- At a cellular level
- In the body as a whole
- Current research
- References
- External links
- Further reading
thumb|Friedrich Miescher Institute on Novartis St. Johann Campus Brain acid soluble protein 1 is a protein that in humans is encoded by the BASP1 gene.
BASP1 (Brain acid soluble protein 1) is a 22Kd, N-terminal Myristoylated protein involved in gene regulation, cytoplasmic signaling in neurons, axon regeneration and a variety of other functions. BASP1 is encoded by the BASP1 gene and is part of the GMC protein family with GAP-43 and MARCKS. Although BASP1 has been mainly identified as a tumor suppressor, upregulation of BASP1 has been seen in several cancers and offers poor prognosis.