BASP1

Also known as CAP-23, CAP23, NAP-22, NAP22, brain abundant membrane attached signal protein 1

thumb|Friedrich Miescher Institute on Novartis St. Johann Campus Brain acid soluble protein 1 is a protein that in humans is encoded by the BASP1 gene.

In the Vinony graph

Within Vinony's link graph, BASP1 is referenced by 4 other articles, and connects out to PubMed, Ensembl genome database project and protein.

It is catalogued under the topic Genes on human chromosome 5.

Its subject is documented across 5 Wikipedia language editions.

Gene data

BASP1

Name: brain abundant membrane attached signal protein 1
Type: protein-coding
Position: 17,065,598–17,276,857 (+)
Aliases: CAP-23, CAP23, NAP-22, NAP22
Ensembl: ENSG00000176788
RefSeq RNA: NM_001271606.2, NM_006317.5
RefSeq protein: NP_001258535.1, NP_006308.3

This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2012].

Pathways

Signal Transduction Signaling by Rho GTPases RHO GTPase cycle RHOF GTPase cycle Signaling by Rho GTPases, Miro GTPases and RHOBTB3

via MyGene.info

Gene · Ensembl

brain abundant membrane attached signal protein 1

Symbol: BASP1
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:17,065,598-17,276,857
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 38168
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/10409
chromosome: human chromosome 5
genomic start: 17065707
genomic end: 17276943
cytogenetic location: 5p15.1
expressed in: occipital lobe

Sources (3)

via Wikidata · CC0

~8 min read

Encyclopedic overview

9 sections

Contents

Discovery
Structure
Function
At a cellular level
In the body as a whole
Current research
References
External links
Further reading

thumb|Friedrich Miescher Institute on Novartis St. Johann Campus Brain acid soluble protein 1 is a protein that in humans is encoded by the BASP1 gene.

BASP1 (Brain acid soluble protein 1) is a 22Kd, N-terminal Myristoylated protein involved in gene regulation, cytoplasmic signaling in neurons, axon regeneration and a variety of other functions. BASP1 is encoded by the BASP1 gene and is part of the GMC protein family with GAP-43 and MARCKS. Although BASP1 has been mainly identified as a tumor suppressor, upregulation of BASP1 has been seen in several cancers and offers poor prognosis.

Excerpted from Wikipedia’s “BASP1” article, available under the CC BY-SA 4.0 licence.