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بنداموستین

Structure via PubChem · Public domain (PubChem)

EntityQ425745· pop 24· linked from 298 articles

بنداموستین

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Also known as Levact®, SDX-105, Treanda®, Ribomustine, Bendamustine

Bendamustine, sold under the brand name Treanda among others, is a chemotherapy medication used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin's lymphoma. It is given by injection into a vein.

Chemical data

Formula
C16H21Cl2N3O2
Molecular weight
358.3 g/mol
IUPAC name
4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
SMILES
CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O
InChIKey
YTKUWDBFDASYHO-UHFFFAOYSA-N
XLogP
2.9
Polar surface area
58.4 Ų
H-bond donors
1
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
2008
Admin. routes
parenteral
Indications
chronic lymphocytic leukemia, multiple myeloma, non-Hodgkins lymphoma, Hodgkins lymphoma

via ChEMBL · EBI

Wikidata facts

Mass
357.101082
Has use
medication
Show 5 more facts
medical condition treated
diffuse large B-cell lymphoma
chemical formula
C₁₆H₂₁Cl₂N₃O₂
canonical SMILES
CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O
Commons category
Bendamustine
subject has role
essential medicine
Sources (4)

via Wikidata · CC0