Bendamustine

Also known as Levact®, SDX-105, Treanda®, Ribomustine

Bendamustine, sold under the brand name Treanda among others, is a chemotherapy medication used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin's lymphoma. It is given by injection into a vein.

In the Vinony graph

Within Vinony's link graph, Bendamustine is referenced by 298 other articles, and connects out to intravenous infusion and defusion, chemotherapy and tiazofurin.

Vinony files it under Benzimidazoles, Chloroethyl compounds and Drugboxes which contain changes to watched fields.

Its subject is documented across 23 Wikipedia language editions.

Chemical data

Formula: C16H21Cl2N3O2
Molecular weight: 358.3 g/mol
IUPAC name: 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
SMILES: CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O
InChIKey: YTKUWDBFDASYHO-UHFFFAOYSA-N
XLogP: 2.9
Polar surface area: 58.4 Å²
H-bond donors: 1
H-bond acceptors: 4
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 2008
Admin. routes: parenteral
Indications: chronic lymphocytic leukemia, multiple myeloma, non-Hodgkins lymphoma, Hodgkins lymphoma

via ChEMBL · EBI