English
benzestrol
Sign in to saveBenzestrol (, ) (brand names Chemestrogen, Ocestrol, Octestrol, Octoestrol, Octofollin) is a synthetic nonsteroidal estrogen of the stilbestrol group which was formerly used medically but has since been discontinued. The stilbestrol estrogens, the best-known of which is diethylstilbestrol (DES) were used extensively in the mid-1900s and were finally banned by the FDA due to them causing tumors in the children of women who used them.
In the Vinony graph
Vinony's link graph records 594 inbound references to benzestrol, and connects out to DDT, (+)-catechin and abiraterone acetate.
It is catalogued under topics including 4-Hydroxyphenyl compounds, Abandoned drugs and Chemical pages without DrugBank identifier.
Vinony links it to 5 Wikipedia language editions.
Wikidata facts
- Mass
- 298.193
Show 3 more facts
- chemical formula
- C₂₀H₂₆O₂
- canonical SMILES
- CCC(C1=CC=C(C=C1)O)C(CC)C(C)C2=CC=C(C=C2)O
- Commons category
- Benzestrol
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
8 sectionsContents
- Medical uses
- Pharmacology
- Pharmacodynamics
- Chemistry
- Synthesis
- History
- See also
- References
Benzestrol (, ) (brand names Chemestrogen, Ocestrol, Octestrol, Octoestrol, Octofollin) is a synthetic nonsteroidal estrogen of the stilbestrol group which was formerly used medically but has since been discontinued. The stilbestrol estrogens, the best-known of which is diethylstilbestrol (DES) were used extensively in the mid-1900s and were finally banned by the FDA due to them causing tumors in the children of women who used them.
==Medical uses== Benzestrol and other stilbestrol were used as synthetic estrogens in order to prevent premature births. Based on the idea that premature births happened because the mother did not produce enough estrogen on her own, doctors prescribed benzestrol to mothers in order to increase their estrogen levels.
Excerpted from Wikipedia’s “benzestrol” article, available under the CC BY-SA 4.0 licence.