BRD8

Also known as SMAP, SMAP2, p120, bromodomain containing 8

Bromodomain-containing protein 8 is a protein that in humans is encoded by the BRD8 gene.

Gene data

BRD8

Name: bromodomain containing 8
Type: protein-coding
Position: 138,139,770–138,178,953 (−)
Aliases: SMAP, SMAP2, p120
Ensembl: ENSG00000112983
RefSeq RNA: NM_001164326.2, NM_001300961.3, NM_001300962.3, NM_001300966.3, NM_006696.5
RefSeq protein: NP_001157798.1, NP_001287890.1, NP_001287891.1, NP_001287895.1, NP_006687.3

The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Multiple alternatively spliced transcript variants that encode distinct isoforms have been identified. [provided by RefSeq, Jul 2014].

Gene Ontology

Biological process

cell surface receptor signaling pathway regulation of apoptotic process

Article

4 sections

Contents

Interactions
References
External links
Further reading

Bromodomain-containing protein 8 is a protein that in humans is encoded by the BRD8 gene.

The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.