Structure via PubChem · Public domain (PubChem)
bucolome
Sign in to saveAlso known as 5-Butyl-1-cyclohexylbarbituric acid, 5-butyl-1-cyclohexyl-2,4,6(1H,3H,5H)-pyrimidinetrione
Bucolome (Paramidine) is a barbiturate derivative. Unlike most barbiturates it does not have any significant sedative or hypnotic effects, but instead acts as an analgesic and antiinflammatory. It also acts as a CYP2C9 inhibitor and reduces the metabolism of several commonly used drugs, which makes it useful for potentiating or extending the duration of action of those drugs, or reducing the production of unwanted metabolites.
In the Vinony graph
Within Vinony's link graph, bucolome is referenced by 2 other articles, and connects out to fenamic acid, cocaine and cannabis.
It is catalogued under topics including Barbiturates, Chemical pages without DrugBank identifier and Cyclohexyl compounds.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C14H22N2O3
- Molecular weight
- 266.34 g/mol
- IUPAC name
- 5-butyl-1-cyclohexyl-1,3-diazinane-2,4,6-trione
- SMILES
- CCCCC1C(=O)NC(=O)N(C1=O)C2CCCCC2
- InChIKey
- DVEQCIBLXRSYPH-UHFFFAOYSA-N
- XLogP
- 2.9
- Polar surface area
- 66.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 266.163
Show 3 more facts
- chemical formula
- C₁₄H₂₂N₂O₃
- canonical SMILES
- CCCCC1C(=O)NC(=O)N(C1=O)C2CCCCC2
- Commons category
- Bucolome
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Bucolome (Paramidine) is a barbiturate derivative. Unlike most barbiturates it does not have any significant sedative or hypnotic effects, but instead acts as an analgesic and antiinflammatory. It also acts as a CYP2C9 inhibitor and reduces the metabolism of several commonly used drugs, which makes it useful for potentiating or extending the duration of action of those drugs, or reducing the production of unwanted metabolites.
== References ==
Excerpted from Wikipedia’s “bucolome” article, available under the CC BY-SA 4.0 licence.