Structure via PubChem · Public domain (PubChem)
bufetolol
Sign in to saveBufetolol is a beta-adrenoceptor antagonist.
In the Vinony graph
Within Vinony's link graph, bufetolol is referenced by 557 other articles, and connects out to propranolol, beta blocker and atenolol.
It sits within the topics Beta blockers, Catechol ethers and Chembox image size set.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C18H29NO4
- Molecular weight
- 323.4 g/mol
- IUPAC name
- 1-(tert-butylamino)-3-[2-(oxolan-2-ylmethoxy)phenoxy]propan-2-ol
- SMILES
- CC(C)(C)NCC(COC1=CC=CC=C1OCC2CCCO2)O
- InChIKey
- AKLNLVOZXMQGSI-UHFFFAOYSA-N
- XLogP
- 2.6
- Polar surface area
- 60 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
13 papers- Beta-adrenoceptor blocking and electrophysiological effects of bufetolol in the guinea pig atria.European journal of pharmacology · 1977
- Effects of bufetolol and propranolol on active and passive membrane properties of dog papillary muscle.Japanese journal of pharmacology · 1976
- Hemodynamic effects of beta-adrenergic blockade with pindolol, oxprenolol, propranolol and bufetolol hydrochloride in essential hypertension.Japanese circulation journal · 1976
- Effects of beta-adrenoceptor blocking agents of N-tertiary butyl derivatives on maximum upstroke velocity of action potential in guinea-pig papillary muscles.Naunyn-Schmiedeberg's archives of pharmacology · 1983
- Presynaptic inhibition by serotonin of cardiac sympathetic transmission in dogs.Clinical and experimental pharmacology & physiology · 1983
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 323.21
Show 3 more facts
- canonical SMILES
- CC(C)(C)NCC(COC1=CC=CC=C1OCC2CCCO2)O
- chemical formula
- C₁₈H₂₉NO₄
- subject has role
- beta blocker
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Bufetolol is a beta-adrenoceptor antagonist.
==References==
Excerpted from Wikipedia’s “bufetolol” article, available under the CC BY-SA 4.0 licence.
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