C1QTNF5

Also known as CTRP5, C1q and tumor necrosis factor related protein 5, C1q and TNF related 5, MFRP

== Protein Summary ==

In the Vinony graph

Vinony's link graph records 3 inbound references to C1QTNF5, and connects out to PubMed, Ensembl genome database project and protein.

It is catalogued under the topic Genes on human chromosome 11.

Vinony links it to 5 Wikipedia language editions.

Gene data

C1QTNF5

Name: C1q and TNF related 5
Type: protein-coding
Position: 119,338,942–119,340,940 (−)
Aliases: CTRP5, MFRP
Ensembl: ENSG00000223953
RefSeq RNA: NM_001278431.2, NM_015645.5
RefSeq protein: NP_001265360.1, NP_056460.1

This gene encodes a member of a family of proteins that function as components of basement membranes and may play a role in cell adhesion. Mutations in this gene have been associated with late-onset retinal degeneration. The protein may be encoded by either a bicistronic transcript including sequence from the upstream membrane frizzled-related protein gene (MFRP), or by a monocistronic transcript expressed from an internal promoter. [provided by RefSeq, Jun 2013].

Gene Ontology

Biological process

signal transduction negative regulation of lipid catabolic process

Molecular function

protein binding signaling receptor inhibitor activity identical protein binding identical protein binding receptor ligand activity

Cellular component

extracellular region extracellular region extracellular region extracellular region plasma membrane plasma membrane bicellular tight junction membrane

via MyGene.info

Gene · Ensembl

C1q and TNF related 5

Symbol: C1QTNF5
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:119,338,942-119,340,940
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 9227
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/114902
chromosome: human chromosome 11
genomic start: 119338942
genomic end: 119217383
cytogenetic location: 11q23.3
expressed in: myometrium

Sources (4)

via Wikidata · CC0

~3 min read

Encyclopedic overview

9 sections

Contents

Protein Summary
Function
Clinical significance
Origin
Structure
Crystal structure
References
Further reading
External links

== Protein Summary ==

C1q and tumor necrosis factor related protein 5, also known as C1QTNF5, is a protein which in humans is encoded by the C1QTNF5 gene, associated with late-onset retinal degeneration( otherwise known as L-ORD). The C1QTNF5 gene secreted and membrane-linked to a protein which is strongly expressed in retinal pigment epithelium cells.

Excerpted from Wikipedia’s “C1QTNF5” article, available under the CC BY-SA 4.0 licence.