Skip to content
Vinony
English
EnglishBahasa IndonesiaDeutschEspañolFrançaisNederlandsPolskiTiếng ViệtTürkçeالعربيةفارسی中文日本語
EntityQ414013· pop 18· linked from 74 articles

carbimazole

Sign in to save

Also known as Athyromazole, Ethyl 3-methyl-2-thioimidazoline-1-carboxylate, Carbethoxymethimazole, Carbimazolo, Carbinazole, Thyrostat, Carbimazol, Carbimazolum

Carbimazole (brand names Neo-Mercazole, Anti-Thyrox, etc.) is used to treat hyperthyroidism. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine).

Research

1,666 papers

via PubMed

Wikidata facts

Subclass of
chemical compound
Mass
186.046299
Has use
medication
Show 7 more facts
chemical formula
C₇H₁₀N₂O₂S
canonical SMILES
CCOC(=O)N1C=CN(C1=S)C
World Health Organisation international non-proprietary name
carbimazole
defined daily dose
15
melting point
124
has characteristic
bitterness
Commons category
Carbimazole
Sources (4)

via Wikidata · CC0

~3 min read

Encyclopedic overview

6 sections
Contents
  • Medical uses
  • Adverse effects
  • Precautions
  • Brand names
  • References
  • Further reading

Carbimazole (brand names Neo-Mercazole, Anti-Thyrox, etc.) is used to treat hyperthyroidism. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine).

It is on the World Health Organization's List of Essential Medicines.

Excerpted from Wikipedia’s “carbimazole” article, available under the CC BY-SA 4.0 licence.

Available in 17 languages

via Wikidata sitelinks · CC0