Structure via PubChem · Public domain (PubChem)
2-Thiouracil
Sign in to saveAlso known as 2-Thio-2,4-(1H,3H)-pyrimidinedione, 2-Thioxo-2,3-dihydro-1H-pyrimidin-4-one, 2-mercapto-4-pyrimidinol, 4-Hydroxy-2-pyrimidinethiol
2-Thiouracil is a chemical derivative of uracil in which the oxygen atom in the 2-position of the ring is substituted by sulfur. It is classified as a thiourea.
Chemical data
- Formula
- C4H4N2OS
- Molecular weight
- 128.15 g/mol
- IUPAC name
- 2-sulfanylidene-1H-pyrimidin-4-one
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- Medical use
- References
2-Thiouracil is a chemical derivative of uracil in which the oxygen atom in the 2-position of the ring is substituted by sulfur. It is classified as a thiourea.
== Medical use == The substance is a historically relevant anti-thyroid preparation. Edwin Astwood used it in 1943 as therapy for Graves' disease for the first time.
Excerpted from Wikipedia’s “2-Thiouracil” article, available under the CC BY-SA 4.0 licence.