cefmenoxime

Also known as (6R,7R)-7-[[(2e)-2-(2-amino-1,3-Thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (iupac), (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure, Cefmenoxima, Cefmenoximum

Cefmenoxime is a third-generation cephalosporin antibiotic.

Key facts

Drug.Verifiedfields: changed
Drug.verifiedrevid: 460023267
Drug.image: Cefmenoxime.svg
Drug.image_class: skin-invert-image
Drug.routes_of_administration: Intramuscular, intravenous
Drug.ATC_prefix: J01
Drug.ATC_suffix: DD05
Drug.ATC_supplemental: ,
Drug.bioavailability: 100% (given IM)
Drug.protein_bound: 50% to 70%
Drug.metabolism: Negligible
Drug.elimination_half life: 1 hour
Drug.excretion: Kidney, unchanged
Drug.CAS_number: 65085-01-0
Drug.PubChem: 9570757
Drug.DrugBank: DB00267
Drug.ChemSpiderID: 7845223
Drug.UNII: KBZ4844CXN

via Wikipedia infobox

Research

535 papers

[Cefmenoxime].The Japanese journal of antibiotics · 1983
Cefmenoxime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.Drugs · 1987
Cefmenoxime: clinical evaluation.The American journal of medicine · 1984
Combination effect of levofloxacin and cefmenoxime against ocular isolates of Pseudomonas aeruginosa.Contact lens & anterior eye : the journal of the British Contact Lens Association · 2024
[Cefmenoxime preparations].The Japanese journal of antibiotics · 1982

via PubMed

Wikidata facts

Mass: 511.051478

Show 6 more facts

chemical formula: C₁₆H₁₇N₉O₅S₃
isomeric SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)O
canonical SMILES: CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O
World Health Organisation international non-proprietary name: cefmenoxime
Commons category: Cefmenoxime
defined daily dose: 2

Sources (3)

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