cefodizime
Sign in to saveAlso known as (6R,7R)-7-{[(22Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, CDZM
Cefodizime is a 3rd generation cephalosporin antibiotic with broad spectrum activity against aerobic gram positive and gram negative bacteria. Clinically, it has been shown to be effective against upper and lower respiratory tract infections, urinary tract infections, and gonorrhea. Cefodizime is a bactericidal antibiotic that targets penicillin-binding proteins (PBPs) 1A/B, 2, and 3 resulting in the eventual death of the bacterial cell. In vivo experimental models of infection showed that bacterial clearance by this drug is at least as effective compared with other 3rd generation cephalospori
Research
303 papers- Cefodizime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.Drugs · 1992
- [Cefodizime].The Japanese journal of antibiotics · 1991
- Safety profile of cefodizime.Infection · 1992
- Pharmacokinetic profile of cefodizime.Infection · 1992
- Cefodizime in clinical use: a review of the clinical trial reports.The Journal of antimicrobial chemotherapy · 1990
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 584.027631
Show 5 more facts
- chemical formula
- C₂₀H₂₀N₆O₇S₄
- canonical SMILES
- CC1=C(SC(=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O)CC(=O)O
- isomeric SMILES
- CC1=C(SC(=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)O)CC(=O)O
- World Health Organisation international non-proprietary name
- cefodizime
- subject has role
- antibiotic
via Wikidata · CC0
~6 min read
Encyclopedic overview
5 sectionsContents
- Efficacy and susceptibility
- Pharmacokinetics
- Adverse effects
- Administration
- References
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| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “cefodizime” article, available under the CC BY-SA 4.0 licence.