Structure via PubChem · Public domain (PubChem)
ceftezole
Sign in to saveCeftezole (or ceftezol) is a semisynthetic first-generation cephalosporin antibiotic.
Chemical data
- Formula
- C13H12N8O4S3
- Molecular weight
- 440.5 g/mol
- IUPAC name
- (6R,7R)-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- SMILES
- C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CN3C=NN=N3)C(=O)O)CSC4=NN=CS4
- InChIKey
- DZMVCVMFETWNIU-LDYMZIIASA-N
- XLogP
- -0.7
- Polar surface area
- 235 Ų
- H-bond donors
- 2
- H-bond acceptors
- 12
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- bacterial disease
via ChEMBL · EBI
Research
45 papers- Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity.International journal of molecular medicine · 2007
- Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration.The Journal of antibiotics · 1976
- Behaviors and physical mechanism of ceftezole sodium de-agglomeration driven by ultrasound.Ultrasonics sonochemistry · 2021
- Ceftezole, a new cephalosporin C derivative I. In vitro and in vivo antimicrobial activity.The Journal of antibiotics · 1976
- Pharmacokinetic studies on ceftezole.Chemioterapia : international journal of the Mediterranean Society of Chemotherapy · 1986
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 440.014
Show 5 more facts
- chemical formula
- C₁₃H₁₂N₈O₄S₃
- canonical SMILES
- C1C(=C(N2C(S1)C(C2=O)NC(=O)CN3C=NN=N3)C(=O)O)CSC4=NN=CS4
- isomeric SMILES
- C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CN3C=NN=N3)C(=O)O)CSC4=NN=CS4
- subject has role
- antibiotic
- Commons category
- Ceftezole
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- References
- Note
- External links
{{Drugbox | Watchedfields = changed | IUPAC_name = (6R,7R)-8-oxo-7-{[2-(tetrazol-1-yl)acetyl]amino}-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | image = ceftezole.png | image_class = skin-invert-image
| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “ceftezole” article, available under the CC BY-SA 4.0 licence.
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