Structure via PubChem · Public domain (PubChem)
ceftibuten
Sign in to saveAlso known as 7432-S, Cedax, Seftem, SCH-39720, cis-Ceftibuten, Ceftibuteno, (+)-(6R,7R)-7-((Z)-2-(2-amino-4-Thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, Ceftibutenum
Ceftibuten is a third-generation cephalosporin antibiotic. It is an orally administered agent, with two dosage forms, capsule or oral suspension. It is marketed by Pernix Therapeutics under the trade name Cedax.
Chemical data
- Formula
- C15H14N4O6S2
- Molecular weight
- 410.4 g/mol
- IUPAC name
- (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- SMILES
- C1C=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=C\CC(=O)O)/C3=CSC(=N3)N)C(=O)O
- InChIKey
- UNJFKXSSGBWRBZ-BJCIPQKHSA-N
- XLogP
- -0.3
- Polar surface area
- 216 Ų
- H-bond donors
- 4
- H-bond acceptors
- 10
- Formal charge
- 0
via PubChem
Research
366 papers- Ceftibuten.2006
- Ceftibuten.Indian pediatrics · 1999
- [Ceftibuten].The Japanese journal of antibiotics · 1993
- Ceftibuten: an overview.Pharmacotherapy · 1997
- Ceftibuten pharmacokinetics and pharmacodynamics. Focus on paediatric use.Clinical pharmacokinetics · 1994
via PubMed
Wikidata facts
- Subclass of
- cephalosporin antibiotic
- Mass
- 410.035476
- Has use
- medication
Show 8 more facts
- chemical formula
- C₁₅H₁₄N₄O₆S₂
- subject has role
- enzyme inhibitor
- medical condition treated
- urinary tract infection
- World Health Organisation international non-proprietary name
- ceftibuten
- isomeric SMILES
- C1C=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=C\CC(=O)O)/C3=CSC(=N3)N)C(=O)O
- canonical SMILES
- C1C=C(N2C(S1)C(C2=O)NC(=O)C(=CCC(=O)O)C3=CSC(=N3)N)C(=O)O
- defined daily dose
- 0.4
- Commons category
- Ceftibuten
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Medical uses
- Adverse effects
- Susceptibility
- References
- External links
Ceftibuten is a third-generation cephalosporin antibiotic. It is an orally administered agent, with two dosage forms, capsule or oral suspension. It is marketed by Pernix Therapeutics under the trade name Cedax.
==Medical uses==
Excerpted from Wikipedia’s “ceftibuten” article, available under the CC BY-SA 4.0 licence.