ceramides
Sign in to saveAlso known as ceramide
thumb|Ceramide. R represents the alkyl portion of a fatty acid. thumb|class=skin-invert|upright=2|General structures of sphingolipids Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid joined by an amide bond. Ceramides are found in high concentrations within the cell membrane of eukaryotic cells, since they are component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer. Contrary to previous assumptions that ceramides and other sphingolipids found in cell membrane were purely supporting structural elements, cera
Research
27,001 papers- Ceramides in Skin Health and Disease: An Update.American journal of clinical dermatology · 2021
- Ceramides and Skin Health: New Insights.Experimental dermatology · 2025
- Ceramides and Acute Kidney Injury.Seminars in nephrology · 2022
- Ceramides as Novel Disease Biomarkers.Trends in molecular medicine · 2019
- Visualizing bioactive ceramides.Chemistry and physics of lipids · 2018
via PubMed
Wikidata facts
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- isomeric SMILES
- O[C@H]([*])[C@H](C[*])NC([*])=O
- chemical formula
- C₃₆H₇₁NO₃
- Commons category
- Ceramides
Sources (2)
via Wikidata · CC0
~12 min read
Article
17 sectionsContents
- Pathways for ceramide synthesis
- Sphingomyelin hydrolysis
- De novo
- Salvage pathway
- Physiological roles
- Pathology
- Apoptosis
- Skin
- Hormonal
- Substances known to induce ceramide generation
- Mechanism by which ceramide signaling occurs
- Related diseases
- Uses
- Ceramide in bacteria
- Ceramide phosphoethanolamine
- References
- External links
thumb|Ceramide. R represents the alkyl portion of a fatty acid. thumb|class=skin-invert|upright=2|General structures of sphingolipids Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid joined by an amide bond. Ceramides are found in high concentrations within the cell membrane of eukaryotic cells, since they are component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer. Contrary to previous assumptions that ceramides and other sphingolipids found in cell membrane were purely supporting structural elements, ceramide can participate in a variety of cellular signaling: examples include regulating differentiation, proliferation, and programmed cell death (PCD) of cells.
The word ceramide comes from the Latin cera (wax) and amide. Ceramide is a component of vernix caseosa, the waxy or cheese-like white substance found coating the skin of newborn human infants.