mucositis
Sign in to saveAlso known as gastrointestinal system mucosaitis, gastrointestinal system mucosa inflammation
Mucositis is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer. Mucositis can occur anywhere along the gastrointestinal (GI) tract, but oral mucositis refers to the particular inflammation and ulceration that occurs in the mouth. Oral mucositis is a common and often debilitating complication of cancer treatment.
Research
379,199 papers- Glutamine for Amelioration of Radiation and Chemotherapy Associated Mucositis during Cancer Therapy.Nutrients · 2020
- The role of mucins in mucositis.Current opinion in supportive and palliative care · 2019
- Understanding chemotherapy-induced intestinal mucositis and strategies to improve gut resilience.American journal of physiology. Gastrointestinal and liver physiology · 2021
- Gastrointestinal mucositis: a sign of a (systemic) inflammatory response.Current opinion in supportive and palliative care · 2024
- Metabolic support protects mucosa from ferroptosis in radiation-induced mucositis.Nature communications · 2025
via PubMed
Wikidata facts
Show 4 more facts
- exact match
- identifiers.org/doid/DOID:0080178
- NCI Thesaurus ID
- C3853
- ICD-9-CM
- 558.9
- Commons category
- Mucositis
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~12 min read
Article
10 sectionsContents
- Signs and symptoms
- Complications
- Pathophysiology
- Diagnosis
- Prevention
- Treatment
- See also
- References
- General sources
- External links
Mucositis is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer. Mucositis can occur anywhere along the gastrointestinal (GI) tract, but oral mucositis refers to the particular inflammation and ulceration that occurs in the mouth. Oral mucositis is a common and often debilitating complication of cancer treatment.
Oral and gastrointestinal (GI) mucositis affects almost all patients undergoing high-dose chemotherapy and hematopoietic stem cell transplantation (HSCT), 80% of patients with cancers of the head and neck receiving radiotherapy, and a wide range of patients receiving chemotherapy. Alimentary tract mucositis increases mortality and morbidity and contributes to rising health care costs.