ChAdOx1
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ChAdOx1 is an adenoviral vector for vaccines that was developed by the Jenner Institute, University of Oxford. The vector is a chimpanzee adenovirus modified to avoid its replication.
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Within Vinony's link graph, ChAdOx1 is referenced by 10 other articles, and connects out to AZD1222, COVID-19 and COVID-19 pandemic.
Vinony files it under Adenoviridae, Clinical trials and COVID-19 vaccines.
Its subject is documented across 6 Wikipedia language editions.
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Encyclopedic overview
3 sectionsContents
- Virology
- Clinical trials
- References
ChAdOx1 is an adenoviral vector for vaccines that was developed by the Jenner Institute, University of Oxford. The vector is a chimpanzee adenovirus modified to avoid its replication.
Adenoviruses are effective vectors for inducing and boosting cellular immunity to encoded recombinant antigens. However, the widespread seroprevalence of neutralizing antibodies to common human adenovirus serotypes limits their use. Simian adenoviruses do not suffer from the same disadvantages. Therefore, investigators have tested new vaccines using the chimp adenovirus ChAdOx1 as a vector. For example, a vaccine for influenza infection was designed using the vector expressing influenza antigens, nucleoprotein (NP), and matrix protein 1 (M1), creating a vaccine candidate named ChAdOx1 NP+M1. __TOC__
Excerpted from Wikipedia’s “ChAdOx1” article, available under the CC BY-SA 4.0 licence.