ciglitazone
Sign in to saveAlso known as (+-)-5-{p-[(1-Methylcyclohexyl)methoxy]benzyl}-2,4-thiazolidinedione
Ciglitazone (INN) is a thiazolidinedione. Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.
Research
627 papers- Anti-fibrotic effect of ciglitazone in HRV-induced airway remodelling cell model.Journal of cellular and molecular medicine · 2023
- Ciglitazone-a human PPARγ agonist-disrupts dorsoventral patterning in zebrafish.PeerJ · 2019
- Effect of ciglitazone on adipogenic transdifferentiation of bovine skeletal muscle satellite cells.Journal of animal science and technology · 2021
- Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth.Cell death and differentiation · 2011
- Ciglitazone enhances ovarian cancer cell death via inhibition of glucose transporter-1.European journal of pharmacology · 2014
via PubMed
Wikidata facts
- Subclass of
- glitazone
- Mass
- 333.139865
Show 4 more facts
- World Health Organisation international non-proprietary name
- 环格列酮
- chemical formula
- C₁₈H₂₃NO₃S
- canonical SMILES
- CC1(CCCCC1)COC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
- subject has role
- anti-diabetic medication
via Wikidata · CC0
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Encyclopedic overview
1 sectionsContents
- References
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| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “ciglitazone” article, available under the CC BY-SA 4.0 licence.