Клатрин
Sign in to saveAlso known as clathrin, GO:0071439, clathrin complex family, clathrin triskelion, Clathrin
Clathrin is a protein that plays a role in the formation of coated vesicles. Clathrin was first isolated by Barbara Pearse in 1976. It forms a triskelion shape composed of three clathrin heavy chains and three light chains. When the triskelia interact they form a polyhedral lattice that surrounds the vesicle. The protein's name refers to this lattice structure, deriving from Latin clathri, meaning lattice. Barbara Pearse named the protein clathrin at the suggestion of Graeme Mitchison, selecting it from three possible options. Coat-proteins, like clathrin, are used to build small vesicles in o
In the Vinony graph
Within Vinony's link graph, Клатрин is referenced by 223 other articles, and connects out to AP-type membrane coat adaptor complex, COPII and spindle.
It is catalogued under topics including Cell biology, Genes on human chromosome 17 and Genes on human chromosome 22.
Its subject is documented across 26 Wikipedia language editions.
Key facts
- Protein family.class
- collapsible
- Protein family.Symbol
- Clathrin_lg_ch
- Protein family.Name
- Clathrin light chain
- Protein family.image
- PDB 1b89 EBI.jpg
- Protein family.caption
- clathrin heavy chain proximal repeat (linker)
- Protein family.Pfam
- PF01086
- Protein family.Pfam_clan
- CL0020
- Protein family.InterPro
- IPR000996
- Protein family.SCOP
- 3iyv
- Protein family.SMART
- SM00299
- Protein family.PROSITE
- PDOC00196
- Protein family.CATH
- 1b89
- Protein.name
- Clathrin light chain a
- Protein.bodyclass
- collapsible collapsed
- Protein.Symbol
- CLTCL1
- Protein.EntrezGene
- 8218
- Protein.HGNCid
- 2093
- Protein.UniProt
- P53675
via Wikipedia infobox
Research
3,850 papers- Regulation of Clathrin-Mediated Endocytosis.Annual review of biochemistry · 2018
- Molecular mechanism and physiological functions of clathrin-mediated endocytosis.Nature reviews. Molecular cell biology · 2011
- Clathrin-dependent endocytosis.The Biochemical journal · 2004
- Clathrin-containing adhesion complexes.The Journal of cell biology · 2019
- Clathrin and adaptors.Biochimica et biophysica acta · 1998
via PubMed
Wikidata facts
Show 2 more facts
- exact match
- purl.obolibrary.org/obo/GO_0071439
- Commons category
- Clathrin
Sources (3)
via Wikidata · CC0
Article · Русский
Клатрин (англ. clathrin) — внутриклеточный белок, основной компонент оболочки окаймлённых пузырьков, образующихся при рецепторном эндоцитозе.
Abstract from DBpedia / Wikipedia · CC BY-SA